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Phenion

3D tissue models of the human skin - Multi-functional tools for in vitro R&D and risk assessmen

TissUse GmbH, Germany, develops innovative microfluidic multi-organ systems with miniaturized Phenion® FT Skin Models as the dermal component

Phenion® FT Skin Models part of the HUMIMIC organ-on-a-chip

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Outlook - Portfolio changes becoming effective 2024, January 1st

Portfolio changes becoming effective 2024, January 1st

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New study published about adverse reactions after hyaluronic acid-based fillers in Phenion Full-Thickness Skin Models

Gene expression analysis after HA filler injections in FT skin model 11_2022

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Phenion has been awarded the „Rheinischer Innovationspreis ‏(Rhineland Innovation Prize)“ for its outstanding engagement in developing and producing 3D tissue models of the human skin for the efficacy and safety assessment of chemicals and formulations.

Innovation Prize for Phenion

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Our Vision

Mission Statement

We provide worldwide best in class tissue engineered 3D skin models. Our artificial skin fulfills diverse in vitro research needs.

Phenion team standing in front of green screens.

Phenion at a glance

Phenion, a brand from Henkel, is a synonym for more than 15 years of state-of-the-art expertise in the development of alternatives to animal testing, in vitro research and tissue engineering. Find our products, e.g. artificial skin models build of both epidermis and dermis with a connective tissue made of collagen as well as of de novo synthesized extracellular matrix (ECM). Download our references and further information in our Information Center!

Discover our products

Petri dish with reconstructed tissues model.

Reconstructed Tissues

The human Phenion Full-Thickness Skin Models mimic native human skin in diverse dimensions, such as histological architecture and a wide spectrum of physiological skin parameters.

Science flasks stacked on top of each other.

Primary Human Skin Cells

Cells derived from the skin tissue are grown in monolayer culture to generate passage 1 cells (P1-cells)

Pipet with bottle.

Cell Culture Media

Phenion cell culture media are developed to serve the delicate nutrition needs for individual cell types and 3-dimensional complex skin tissues.

Phenion adapter for Franz cells

The innovative adapter module is designed to place the Phenion® Full-Thickness Skin Model precisely in the center of a Franz Cell.

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Our partners

Phenion-partner-dermatest

www.dermatest.de

Find out more about Dermatest.

Phenion-partner-instem

Find out more about Instem.

www.courage-khazaka.de

Find out more about Courage + Khazaka electronic GmbH.

Find out more about 3Helix Inc.

Find out more about Charles River.

Our partners

"We appreciate the insert-free tissue culture which offers us maximum freedom for substance application and analytical procedures. The models can be easily handled in our labs due to their robustness and, what is most important, display excellent morphological and physiological properties. That’s why the Phenion® Full-Thickness Skin Model is an essential tool in Dermatest’s in vitro test portfolio."

Dr. Lars Rüther, Study Director Dermatest GmbH, Germany

“I want to congratulate you for the quality of your products and the easy handling of them”

C. Estornut, University of Valencia, Spain

“Thanks a lot for your great support! I have used your skin models ‏(OS-REp) for the first time in our tests, and it went along very well! We will continue working with the Phenion models!”

Dr. Silke Lohan, Charité – Universitätsmedizin Berlin, Germany

About Henkel

Building on a strong legacy of more than 145 years, we are leading the way to reimagine and improve life every day. Today and for generations to come. Through innovative and sustainable brands and technologies, across our teams around the world.

Henkel holds leading positions in both industrial and consumer businesses: Our portfolio includes well-known hair care products, laundry detergents, fabric softeners as well as adhesives, sealants, and functional coatings.

Read more about our company.

Henkel Corporate Scientific Solutions

Your Scientific Competence and Service Center. All available services can be found on the CSS website.